CHAPTER OUTLINE

1. SPECIMEN ADEQUACY
    
   • Squamous cellularity
     • Unsatisfactory
     • Satisfactory
   • Transformation zone component
   • Obscuring factors
   
   
2. NON-NEOPLASTIC FINDINGS
    
   • Organisms
     • Trichomonas vaginalis
     • Fungal organisms morphologically consistent with Candida spp
     • Shift in flora suggestive of bacterial vaginosis
     • Bacteria morphologically consistent with Actinomyces spp
     • Cellular changes consistent with Herpes simplex virus
   • Other non-neoplastic findings (Optional to report; list not inclusive)
     • Reactive cellular changes associated with:
       • Inflammation (includes typical repair)
       • Radiation
       • Intrauterine contraceptive device (IUD)
     • Glandular cells status post hysterectomy
     • Atrophy
     • Non-neoplastic findings, not specifically listed in 2001 Bethesda terminology
       • Tubal metaplasia
       • Keratotic cellular changes
       • Lymphocytic (follicular) cervicitis
       • Other
   
   
3. ENDOMETRIAL CELLS (in a woman >= 40 years of age)
    
4. ATYPICAL SQUAMOUS CELLS
    
   • Of undetermined significance (ASC-US)
   • Cannot exclude HSIL (ASC-H)
   
   
5. EPITHELIAL ABNORMALITIES: SQUAMOUS
    
   • Low grade squamous intraepithelial lesion (LSIL)
     Encompassing: HPV/mild dysplasia/CIN 1
   • High grade squamous intraepithelial lesion (HSIL)
     Encompassing: moderate and severe dysplasia, CIS; CIN 2 and CIN 3
     • With features suspicious for invasion (if invasion is suspected)
   • Squamous cell carcinoma
   • Squamous epithelial abnormalities, not specifically listed in 2001 Bethesda terminology
     • Keratinizing lesions
     • Squamous intraepithelial lesions (SIL) - borderline cases
     • SIL with gland involvement
   
   
6. EPITHELIAL ABNORMALITIES: GLANDULAR
    
   • Atypical
     • Endocervical cells, NOS or specify in comments
     • Endometrial cells, NOS or specify in comments
     • Glandular cells, NOS or specify in comments
   • Atypical
     • Endocervical cells, favor neoplastic
     • Glandular cells, favor neoplastic
   • Endocervical adenocarcinoma in situ
   • Adenocarcinoma
     • Endocervical
     • Endometrial
     • Extrauterine
     • Not otherwise specified (NOS)
   
   
7. OTHER MALIGNANT NEOPLASMS
    
   • Carcinomas
   • Sarcomas
   • Other tumors
   
   
8. ANAL CYTOLOGY
    
   • Unsatisfactory
   • NILM: Negative for intraepithelial lesion or malignancy
   • Epithelial cell abnormalities
   
   
9. ANCILLARY TESTING
    
10. COMPUTER ASSISTED INTERPRETATION
     
11. EDUCATIONAL NOTES AND SUGGESTIONS