Archive Item Code: 3200-B
Item Name: Pitfalls in Liver Fine Needle Aspiration
Presentation date: May 25, 2010; Expires: May 25, 2013
Liver fine needle aspiration FNA has become the mainstay for evaluating hepatic lesions. It is often done utilizing computed tomography as an imaging technique. The cytopathologist evaluating these aspirates on site has an important role in diagnosis such lesions.
Pitfalls in liver cytopathology could arise from several potential problems. Recognizing normal liver cytology and the reactive changes (such as hepatitis and cirrhosis) will help avoiding problems of over calling these conditions. Distinguishing well differentiated hepatocellular carcinoma from benign lesions is important in not missing these lesions as benign. The 3rd pitfall is related to distinguishing the less differentiated hepatocellular carcinoma from metastatic lesions. Utilizing immunohistochemical stain is an important aid in resolving this problem.